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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Ngly1em4Lutzy
endonuclease-mediated mutation 4, Cathy Lutz
MGI:5614022
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		Ngly1em4Lutzy/Ngly1em4Lutzy C57BL/6J-Ngly1em4Lutzy/J MGI:5752810


Genotype
MGI:5752810
hm1
Allelic
Composition		 Ngly1em4Lutzy/Ngly1em4Lutzy
Genetic
Background		 C57BL/6J-Ngly1em4Lutzy/J
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Ngly1em4Lutzy mutation (1 available); any Ngly1 mutation (40 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
mortality/aging
postnatal lethality, complete penetrance ( J:101977 )
• 20% of homozygotes are born, but die within 1-2 days
perinatal lethality, incomplete penetrance ( J:101977 )
• homozygotes appear viable in the expected ratios to E18, however, only 20% are born




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
09/30/2025
MGI 6.24 		The Jackson Laboratory