Phenotypes associated with this allele

• Allele Symbol: Cox5b^{tm2b(EUCOMM)Hmgu}
• Allele Name: targeted mutation 2b, Helmholtz Zentrum Muenchen GmbH
• Allele ID: MGI:5613669
• Summary: 2 genotypes

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Cox5b^tm2b(EUCOMM)Hmgu/Cox5b^tm2b(EUCOMM)Hmgu	C57BL/6N-Cox5b^tm2b(EUCOMM)Hmgu/Bay	MGI:5767612
ht2	Cox5b^tm2b(EUCOMM)Hmgu/Cox5b^+	C57BL/6N-Cox5b^tm2b(EUCOMM)Hmgu/Bay	MGI:5797445

Genotype
MGI:5767612

hm1

• Allelic Composition: Cox5b^{tm2b(EUCOMM)Hmgu}/Cox5b^{tm2b(EUCOMM)Hmgu}
• Genetic Background: C57BL/6N-Cox5b^{tm2b(EUCOMM)Hmgu}/Bay
• Cell Lines: HEPD0817_8_E08

Data Sources

IMPC Data for Cox5b

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

integument

pallor ( J:211773 )

♂

IMPC - BCM

limbs/digits/tail

abnormal embryonic autopod plate morphology ( J:211773 )

♂

IMPC - BCM

liver/biliary system

abnormal liver size ( J:211773 )

♂

IMPC - BCM

pale liver ( J:211773 )

♂

IMPC - BCM

mortality/aging

prenatal lethality prior to heart atrial septation ( J:211773 )

IMPC - BCM

preweaning lethality, complete penetrance ( J:211773 )

IMPC - BCM

Genotype
MGI:5797445

ht2

• Allelic Composition: Cox5b^{tm2b(EUCOMM)Hmgu}/Cox5b⁺
• Genetic Background: C57BL/6N-Cox5b^{tm2b(EUCOMM)Hmgu}/Bay
• Cell Lines: HEPD0817_8_E08

Data Sources

IMPC Data for Cox5b

behavior/neurological

unresponsive to tactile stimuli ( J:211773 )

IMPC - BCM

integument

abnormal skin coloration ( J:211773 )

♂

IMPC - BCM

vision/eye

persistence of hyaloid vascular system ( J:211773 )

♂

IMPC - BCM