Phenotypes associated with this allele

• Allele Symbol: Zfp445^{tm1b(EUCOMM)Hmgu}
• Allele Name: targeted mutation 1b, Helmholtz Zentrum Muenchen GmbH
• Allele ID: MGI:5613658
• Summary: 2 genotypes

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Zfp445^tm1b(EUCOMM)Hmgu/Zfp445^tm1b(EUCOMM)Hmgu	C57BL/6N-Zfp445^tm1b(EUCOMM)Hmgu/Ieg	MGI:6263918
ht2	Zfp445^tm1b(EUCOMM)Hmgu/Zfp445^+	C57BL/6N-Zfp445^tm1b(EUCOMM)Hmgu/Ieg	MGI:6263917

Genotype
MGI:6263918

hm1

• Allelic Composition: Zfp445^{tm1b(EUCOMM)Hmgu}/Zfp445^{tm1b(EUCOMM)Hmgu}
• Genetic Background: C57BL/6N-Zfp445^{tm1b(EUCOMM)Hmgu}/Ieg
• Cell Lines: HEPD0692_3_F12

Data Sources

IMPC Data for Zfp445

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

hematopoietic system

increased red blood cell distribution width ( J:211773 )

♀

IMPC - HMGU

homeostasis/metabolism

increased circulating calcium level ( J:211773 )

♀

IMPC - HMGU

mortality/aging

preweaning lethality, incomplete penetrance ( J:211773 )

IMPC - HMGU

nervous system

abnormal brain morphology ( J:211773 )

♀

IMPC - HMGU

vision/eye

decreased total retina thickness ( J:211773 )

♀

IMPC - HMGU

Genotype
MGI:6263917

ht2

• Allelic Composition: Zfp445^{tm1b(EUCOMM)Hmgu}/Zfp445⁺
• Genetic Background: C57BL/6N-Zfp445^{tm1b(EUCOMM)Hmgu}/Ieg
• Cell Lines: HEPD0692_3_F12

Data Sources

IMPC Data for Zfp445

behavior/neurological

decreased grip strength ( J:211773 )

♂

IMPC - HMGU

hearing/vestibular/ear

abnormal auditory brainstem response ( J:211773 )

IMPC - HMGU

vision/eye

decreased total retina thickness ( J:211773 )

♂

IMPC - HMGU