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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Aqp4tm1.1Mysi
targeted mutation 1.1, Masato Yasui
MGI:5613228
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		Aqp4tm1.1Mysi/Aqp4tm1.1Mysi involves: C57BL/6JJcl * C57BL/6NCrlj * CBA/JNCrlj MGI:5613238


Genotype
MGI:5613238
hm1
Allelic
Composition		 Aqp4tm1.1Mysi/Aqp4tm1.1Mysi
Genetic
Background		 involves: C57BL/6JJcl * C57BL/6NCrlj * CBA/JNCrlj
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Aqp4tm1.1Mysi mutation (0 available); any Aqp4 mutation (45 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
hematopoietic system
abnormal microglial cell physiology ( J:214906 )
• the number of proliferating activated microglia cells around the stab wound is reduced compare with wild-type samples

immune system
abnormal microglial cell physiology ( J:214906 )
• the number of proliferating activated microglia cells around the stab wound is reduced compare with wild-type samples

nervous system
abnormal microglial cell physiology ( J:214906 )
• the number of proliferating activated microglia cells around the stab wound is reduced compare with wild-type samples

cellular
abnormal microglial cell physiology ( J:214906 )
• the number of proliferating activated microglia cells around the stab wound is reduced compare with wild-type samples




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
09/30/2025
MGI 6.24 		The Jackson Laboratory