All Phenotypes Rr29<tm1.1Bobh> MGI Mouse

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Phenotypes associated with this allele

Allele Symbol
Allele Name
Allele ID

Rr29^tm1.1Bobh
targeted mutation 1.1, Robert E Hill
MGI:5613147

Summary

2 genotypes

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Rr29^tm1.1Bobh/Rr29^tm1.1Bobh	involves: 129P2/OlaHsd	MGI:5613157
cx2	Rr29^tm1.1Bobh/Rr29⁺ Shh^tm1Chg/Shh⁺	involves: 129P2/OlaHsd * 129S1/Sv * 129X1/SvJ	MGI:5613161

Allelic Composition	Rr29^tm1.1Bobh/Rr29^tm1.1Bobh
Genetic Background	involves: 129P2/OlaHsd

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Rr29^tm1.1Bobh mutation (0 available); any Rr29 mutation (2 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

limbs/digits/tail

oligodactyly ( J:208849 )

• 23% of mice have 4 digits, 27% have 4 phalanges and 3 metatarsels, 41% have 3 digits and 9% have 3 sets of phalanges and 2 metatarsels

abnormal tarsal bone morphology ( J:208849 )

• loss or fusion of tarsals

fused tarsal bones ( J:208849 )

short forelimb ( J:208849 )

• severe forelimb truncations

abnormal hindlimb zeugopod morphology ( J:208849 )

• range of hind limb phenotypes including thickening, shortening and often fusions of the tibia and fibula

abnormal metatarsal bone morphology ( J:208849 )

• loss of metatarsals often showing fusions

fused metatarsal bones ( J:208849 )

skeleton

abnormal tarsal bone morphology ( J:208849 )

• loss or fusion of tarsals

fused tarsal bones ( J:208849 )

abnormal metatarsal bone morphology ( J:208849 )

• loss of metatarsals often showing fusions

fused metatarsal bones ( J:208849 )

Allelic Composition	Rr29^tm1.1Bobh/Rr29⁺ Shh^tm1Chg/Shh⁺
Genetic Background	involves: 129P2/OlaHsd * 129S1/Sv * 129X1/SvJ

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Rr29^tm1.1Bobh mutation (0 available); any Rr29 mutation (2 available)
Shh^tm1Chg mutation (1 available); any Shh mutation (45 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

limbs/digits/tail

abnormal limb morphology ( J:208849 )

• range of limb phenotypes similar to mice homozygous for Rr29^tm1.1Bobh

oligodactyly ( J:208849 )

• 40% of mice have 4 digits, 30% have 4 phalanges and 3 metatarsels, 10% have 3 digits and 20% have 3 sets of phalanges and 2 metatarsels

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