Phenotypes associated with this allele

• Allele Symbol: Rspo3^tm1.1Arte
• Allele Name: targeted mutation 1.1, TaconicArtemis
• Allele ID: MGI:5609537
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Rspo3^tm1.1Arte/Rspo3^tm1.1Arte	either: (involves: C57BL/6) or (involves: C57BL/6 * CD-1)	MGI:5609556

Genotype
MGI:5609556

hm1

• Allelic Composition: Rspo3^tm1.1Arte/Rspo3^tm1.1Arte
• Genetic Background: either: (involves: C57BL/6) or (involves: C57BL/6 * CD-1)

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

embryo

abnormal vitelline vasculature morphology ( J:215739 )

• underdeveloped

embryonic growth arrest ( J:215739 )

• around E10

abnormal placenta morphology ( J:215739 )

• pale without invasion of the labyrinth layer by embryonic blood vessels

• embryonic blood vessels in the placenta fail to undergo proliferation and remodeling

• however, the primary capillary plexus forms and vessels appear normal at E9.5

pale yolk sac ( J:215739 )

cardiovascular system

abnormal angiogenesis ( J:215739 )

• embryonic blood vessels in the placenta fail to undergo proliferation and remodeling

• however, the primary capillary plexus forms and vessels appear normal at E9.5

abnormal vitelline vasculature morphology ( J:215739 )

• underdeveloped

hemorrhage ( J:215739 )

• in embryos