Phenotypes associated with this allele

• Allele Symbol: Pptc7^{tm1b(EUCOMM)Hmgu}
• Allele Name: targeted mutation 1b, Helmholtz Zentrum Muenchen GmbH
• Allele ID: MGI:5609359
• Summary: 2 genotypes

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Pptc7^tm1b(EUCOMM)Hmgu/Pptc7^tm1b(EUCOMM)Hmgu	C57BL/6N-Pptc7^tm1b(EUCOMM)Hmgu/Bay	MGI:6263220
ht2	Pptc7^tm1b(EUCOMM)Hmgu/Pptc7^+	C57BL/6N-Pptc7^tm1b(EUCOMM)Hmgu/Bay	MGI:6288668

Genotype
MGI:6263220

hm1

• Allelic Composition: Pptc7^{tm1b(EUCOMM)Hmgu}/Pptc7^{tm1b(EUCOMM)Hmgu}
• Genetic Background: C57BL/6N-Pptc7^{tm1b(EUCOMM)Hmgu}/Bay
• Cell Lines: HEPD0761_8_C11

Data Sources

IMPC Data for Pptc7

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

behavior/neurological

unresponsive to tactile stimuli ( J:211773 )

IMPC - BCM

embryo

abnormal embryo size ( J:211773 )

♀

IMPC - BCM

growth/size/body

abnormal embryo size ( J:211773 )

♀

IMPC - BCM

mortality/aging

preweaning lethality, incomplete penetrance ( J:211773 )

IMPC - BCM

Genotype
MGI:6288668

ht2

• Allelic Composition: Pptc7^{tm1b(EUCOMM)Hmgu}/Pptc7⁺
• Genetic Background: C57BL/6N-Pptc7^{tm1b(EUCOMM)Hmgu}/Bay
• Cell Lines: HEPD0761_8_C11

Data Sources

IMPC Data for Pptc7

behavior/neurological

unresponsive to tactile stimuli ( J:211773 )

IMPC - BCM

integument

abnormal coat appearance ( J:211773 )

♂

IMPC - BCM