Phenotypes associated with this allele

• Allele Symbol: Meis1^{tm1b(EUCOMM)Hmgu}
• Allele Name: targeted mutation 1b, Helmholtz Zentrum Muenchen GmbH
• Allele ID: MGI:5609342
• Summary: 2 genotypes

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Meis1^tm1b(EUCOMM)Hmgu/Meis1^tm1b(EUCOMM)Hmgu	C57BL/6N-Meis1^tm1b(EUCOMM)Hmgu/J	MGI:6262867
ht2	Meis1^tm1b(EUCOMM)Hmgu/Meis1^+	C57BL/6N-Meis1^tm1b(EUCOMM)Hmgu/J	MGI:6288572

Genotype
MGI:6262867

hm1

• Allelic Composition: Meis1^{tm1b(EUCOMM)Hmgu}/Meis1^{tm1b(EUCOMM)Hmgu}
• Genetic Background: C57BL/6N-Meis1^{tm1b(EUCOMM)Hmgu}/J
• Cell Lines: HEPD0632_4_F11

Data Sources

IMPC Data for Meis1

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

mortality/aging

preweaning lethality, complete penetrance ( J:211773 )

IMPC - JAX

Genotype
MGI:6288572

ht2

• Allelic Composition: Meis1^{tm1b(EUCOMM)Hmgu}/Meis1⁺
• Genetic Background: C57BL/6N-Meis1^{tm1b(EUCOMM)Hmgu}/J
• Cell Lines: HEPD0632_4_F11

Data Sources

IMPC Data for Meis1

behavior/neurological

increased startle reflex ( J:211773 )

♂

IMPC - JAX

hyperactivity ( J:211773 )

♂

IMPC - JAX

nervous system

decreased prepulse inhibition ( J:211773 )

IMPC - JAX

skeleton

increased bone mineral content ( J:211773 )

♀

IMPC - JAX