Phenotypes associated with this allele

• Allele Symbol: Plcl1^tm2.1Matk
• Allele Name: targeted mutation 2.1, Matilda Katan
• Allele ID: MGI:5607952
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Plcl1^tm2.1Matk/Plcl1^tm2.1Matk	FVB.Cg-Plcl1^tm2.1Matk	MGI:5607956

Genotype
MGI:5607956

hm1

• Allelic Composition: Plcl1^tm2.1Matk/Plcl1^tm2.1Matk
• Genetic Background: FVB.Cg-Plcl1^tm2.1Matk

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

Increase in TPA-induced skin proliferation in Plcl1^tm1.1Matk/Plcl1^tm1.1Matk and Plcl1^tm2.1Matk/Plcl1^tm2.1Matk mice

neoplasm

increased incidence of tumors by chemical induction ( J:207384 )

• increase in tumor incidence but not tumor volume in a 2-stage (DMBA and TPA) chemical skin carcinogenesis model

homeostasis/metabolism

increased incidence of tumors by chemical induction ( J:207384 )

• increase in tumor incidence but not tumor volume in a 2-stage (DMBA and TPA) chemical skin carcinogenesis model