All Phenotypes Plcl1<tm2.1Matk> MGI Mouse

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Phenotypes associated with this allele

Allele Symbol
Allele Name
Allele ID

Plcl1^tm2.1Matk
targeted mutation 2.1, Matilda Katan
MGI:5607952

Summary

1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Plcl1^tm2.1Matk/Plcl1^tm2.1Matk	FVB.Cg-Plcl1^tm2.1Matk	MGI:5607956

Allelic Composition	Plcl1^tm2.1Matk/Plcl1^tm2.1Matk
Genetic Background	FVB.Cg-Plcl1^tm2.1Matk

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Plcl1^tm2.1Matk mutation (0 available); any Plcl1 mutation (54 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

Increase in TPA-induced skin proliferation in Plcl1^tm1.1Matk/Plcl1^tm1.1Matk and Plcl1^tm2.1Matk/Plcl1^tm2.1Matk mice

neoplasm

• increase in tumor incidence but not tumor volume in a 2-stage (DMBA and TPA) chemical skin carcinogenesis model

homeostasis/metabolism

• increase in tumor incidence but not tumor volume in a 2-stage (DMBA and TPA) chemical skin carcinogenesis model

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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