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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Inpp5dm2Btlr
mutation 2, Bruce Beutler
MGI:5607764
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		Inpp5dm2Btlr/Inpp5dm2Btlr C57BL/6J-Inpp5dm2Btlr MGI:5607765


Genotype
MGI:5607765
hm1
Allelic
Composition		 Inpp5dm2Btlr/Inpp5dm2Btlr
Genetic
Background		 C57BL/6J-Inpp5dm2Btlr
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Inpp5dm2Btlr mutation (1 available); any Inpp5d mutation (95 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
hematopoietic system
decreased B cell number ( J:216053 )
• mice homozygous for this mutation exhibit a reduced frequency of B cells, including IgD+ and IgM+ B cells, in the peripheral blood.

immune system
decreased B cell number ( J:216053 )
• mice homozygous for this mutation exhibit a reduced frequency of B cells, including IgD+ and IgM+ B cells, in the peripheral blood.




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
09/30/2025
MGI 6.24 		The Jackson Laboratory