Phenotypes associated with this allele
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| Find Mice |
Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Nlrp3M6Btlr mutation
(0 available);
any
Nlrp3 mutation
(61 available)
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immune system
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• mice treated with recombinant human myelin oligodendrocyte glycoprotein exhibit reduced disease severity, reduced recruitment of lymphocytes, monocyte-microglia and natural killer cells to the spinal cord compared with wild-type mice
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|
|
| Find Mice |
Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Nlrp3M6Btlr mutation
(0 available);
any
Nlrp3 mutation
(61 available)
|
|
|
immune system
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• mice bearing this mutation exhibit attenuated inflammatory responses related to decreased secretion of the proinflammatory cytokine interleukin- (IL-) 1 beta in response to priming with lipopolysaccharide (LPS) followed by nigericin treatment.
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Analysis Tools