Phenotypes associated with this allele

• Allele Symbol: Tox^{tm1b(KOMP)Wtsi}
• Allele Name: targeted mutation 1b, Wellcome Trust Sanger Institute
• Allele ID: MGI:5605811
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Tox^tm1b(KOMP)Wtsi/Tox^tm1b(KOMP)Wtsi	C57BL/6N-Tox^tm1b(KOMP)Wtsi/Tcp	MGI:6263750

Genotype
MGI:6263750

hm1

• Allelic Composition: Tox^{tm1b(KOMP)Wtsi}/Tox^{tm1b(KOMP)Wtsi}
• Genetic Background: C57BL/6N-Tox^{tm1b(KOMP)Wtsi}/Tcp
• Cell Lines: EPD0570_4_B05

Data Sources

IMPC Data for Tox

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

behavior/neurological

abnormal startle reflex ( J:211773 )

IMPC - UCD

cardiovascular system

abnormal heart morphology ( J:211773 )

♀

IMPC - UCD

enlarged heart ( J:211773 )

♀

IMPC - UCD

prolonged RR interval ( J:211773 )

IMPC - UCD

growth/size/body

enlarged heart ( J:211773 )

♀

IMPC - UCD

increased spleen weight ( J:211773 )

♂

IMPC - UCD

hearing/vestibular/ear

abnormal auditory brainstem response ( J:211773 )

IMPC - UCD

hematopoietic system

increased spleen weight ( J:211773 )

♂

IMPC - UCD

homeostasis/metabolism

decreased circulating cholesterol level ( J:211773 )

♂

IMPC - UCD

increased circulating alkaline phosphatase level ( J:211773 )

♀

IMPC - UCD

immune system

increased spleen weight ( J:211773 )

♂

IMPC - UCD

nervous system

decreased prepulse inhibition ( J:211773 )

IMPC - UCD

skeleton

decreased bone mineral content ( J:211773 )

♀

IMPC - UCD

decreased bone mineral density ( J:211773 )

♀

IMPC - UCD