Phenotypes associated with this allele

• Allele Symbol: Fbxo22^{tm1b(EUCOMM)Wtsi}
• Allele Name: targeted mutation 1b, Wellcome Trust Sanger Institute
• Allele ID: MGI:5605802
• Summary: 2 genotypes

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Fbxo22^tm1b(EUCOMM)Wtsi/Fbxo22^tm1b(EUCOMM)Wtsi	C57BL/6N-Fbxo22^tm1b(EUCOMM)Wtsi/Nju	MGI:5797532
ht2	Fbxo22^tm1b(EUCOMM)Wtsi/Fbxo22^+	C57BL/6N-Fbxo22^tm1b(EUCOMM)Wtsi/Nju	MGI:6288464

Genotype
MGI:5797532

hm1

• Allelic Composition: Fbxo22^{tm1b(EUCOMM)Wtsi}/Fbxo22^{tm1b(EUCOMM)Wtsi}
• Genetic Background: C57BL/6N-Fbxo22^{tm1b(EUCOMM)Wtsi}/Nju
• Cell Lines: EPD0183_3_A10

Data Sources

IMPC Data for Fbxo22

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

behavior/neurological

decreased grip strength ( J:211773 )

♀

IMPC - MARC

limbs/digits/tail

abnormal tail morphology ( J:211773 )

♀

IMPC - MARC

nervous system

decreased prepulse inhibition ( J:211773 )

♀

IMPC - MARC

reproductive system

female infertility ( J:211773 )

♀

IMPC - MARC

male infertility ( J:211773 )

♂

IMPC - MARC

Genotype
MGI:6288464

ht2

• Allelic Composition: Fbxo22^{tm1b(EUCOMM)Wtsi}/Fbxo22⁺
• Genetic Background: C57BL/6N-Fbxo22^{tm1b(EUCOMM)Wtsi}/Nju
• Cell Lines: EPD0183_3_A10

Data Sources

IMPC Data for Fbxo22

cardiovascular system

decreased heart left ventricle size ( J:211773 )

IMPC - MARC

thin ventricular wall ( J:211773 )

IMPC - MARC