Phenotypes associated with this allele

• Allele Symbol: Riok2^{tm1b(KOMP)Wtsi}
• Allele Name: targeted mutation 1b, Wellcome Trust Sanger Institute
• Allele ID: MGI:5605779
• Summary: 2 genotypes

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Riok2^tm1b(KOMP)Wtsi/Riok2^tm1b(KOMP)Wtsi	C57BL/6N-Riok2^tm1b(KOMP)Wtsi/Tcp	MGI:6263375
ht2	Riok2^tm1b(KOMP)Wtsi/Riok2^+	C57BL/6N-Riok2^tm1b(KOMP)Wtsi/Tcp	MGI:5884026

Genotype
MGI:6263375

hm1

• Allelic Composition: Riok2^{tm1b(KOMP)Wtsi}/Riok2^{tm1b(KOMP)Wtsi}
• Genetic Background: C57BL/6N-Riok2^{tm1b(KOMP)Wtsi}/Tcp
• Cell Lines: EPD0882_5_F07

Data Sources

IMPC Data for Riok2

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

mortality/aging

embryonic lethality prior to organogenesis ( J:211773 )

IMPC - TCP

prenatal lethality prior to heart atrial septation ( J:211773 )

IMPC - TCP

preweaning lethality, incomplete penetrance ( J:211773 )

IMPC - UCD

Genotype
MGI:5884026

ht2

• Allelic Composition: Riok2^{tm1b(KOMP)Wtsi}/Riok2⁺
• Genetic Background: C57BL/6N-Riok2^{tm1b(KOMP)Wtsi}/Tcp
• Cell Lines: EPD0882_5_F07

Data Sources

IMPC Data for Riok2

cardiovascular system

enlarged heart ( J:211773 )

♂

IMPC - UCD

growth/size/body

enlarged heart ( J:211773 )

♂

IMPC - UCD

homeostasis/metabolism

increased circulating bilirubin level ( J:211773 )

♀

IMPC - UCD

increased circulating alanine transaminase level ( J:211773 )

♀

IMPC - UCD

increased circulating aspartate transaminase level ( J:211773 )

♀

IMPC - UCD