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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		S100a5tm1.1Mom
targeted mutation 1.1, Peter Mombaerts
MGI:5605391
Summary 2 genotypes
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		S100a5tm1.1Mom/S100a5tm1.1Mom involves: 129P2/OlaHsd * C57BL/6J * FVB/N MGI:5605396
cx2
 		Cnga2tm1Mom/Cnga2tm1Mom
S100a5tm1.1Mom/? 		involves: 129P2/OlaHsd * C57BL/6J * FVB/N MGI:5605395


Genotype
MGI:5605396
hm1
Allelic
Composition		 S100a5tm1.1Mom/S100a5tm1.1Mom
Genetic
Background		 involves: 129P2/OlaHsd * C57BL/6J * FVB/N
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
S100a5tm1.1Mom mutation (1 available); any S100a5 mutation (7 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
normal phenotype
no abnormal phenotype detected ( J:215302 )
• Homozygotes are indistinguishable from wild-type littermates




Genotype
MGI:5605395
cx2
Allelic
Composition		 Cnga2tm1Mom/Cnga2tm1Mom
S100a5tm1.1Mom/?
Genetic
Background		 involves: 129P2/OlaHsd * C57BL/6J * FVB/N
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Cnga2tm1Mom mutation (2 available); any Cnga2 mutation (15 available)
S100a5tm1.1Mom mutation (1 available); any S100a5 mutation (7 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
nervous system
abnormal olfactory sensory neuron physiology ( J:215302 )
• S100A5 driven GFP fluorescence is nearly undetectable in odorant stimulated olfactory sensory neurons null for CNGA2 indicating that CNGA2 is required for activation of S100A5

taste/olfaction
abnormal olfactory sensory neuron physiology ( J:215302 )
• S100A5 driven GFP fluorescence is nearly undetectable in odorant stimulated olfactory sensory neurons null for CNGA2 indicating that CNGA2 is required for activation of S100A5

respiratory system
abnormal olfactory sensory neuron physiology ( J:215302 )
• S100A5 driven GFP fluorescence is nearly undetectable in odorant stimulated olfactory sensory neurons null for CNGA2 indicating that CNGA2 is required for activation of S100A5




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
04/23/2024
MGI 6.23 		The Jackson Laboratory