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Allele Symbol Allele Name Allele ID |
Tg(CD2-Mir181d)38Oers transgene insertion 38, Nicolai S C van Oers MGI:5588400 |
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| Summary |
2 genotypes
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| ♀ | phenotype observed in females |
| ♂ | phenotype observed in males |
| N | normal phenotype |
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• dramatic reduction in the periphery
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• dramatic reduction in the periphery
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| ♀ | phenotype observed in females |
| ♂ | phenotype observed in males |
| N | normal phenotype |
| N |
• mice exhibit normal proportion and numbers of gamma-delta T cell and NK1.1 cells
• the rate of cell death of double positive thymocytes is normal
• peripheral B220+ B cell percentages are normal
• T cell function after egress from the thymus is normal
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• augmented stress-induced thymic atrophy using dexamethasone
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• slightly in the periphery
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• percent and number in untreated mice
• in LPS- or dexamethasone-treated mice
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• reduced percentage and numbers of mature CD4-CD8+ T cells in lymph nodes and spleen
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• augmented stress-induced thymic atrophy using dexamethasone
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• augmented stress-induced thymic atrophy using dexamethasone
|
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• slightly in the periphery
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• percent and number in untreated mice
• in LPS- or dexamethasone-treated mice
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• reduced percentage and numbers of mature CD4-CD8+ T cells in lymph nodes and spleen
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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 05/07/2024 MGI 6.23 |
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