Phenotypes associated with this allele

• Allele Symbol: Gdi2^{tm1b(EUCOMM)Hmgu}
• Allele Name: targeted mutation 1b, Helmholtz Zentrum Muenchen GmbH
• Allele ID: MGI:5588293
• Summary: 2 genotypes

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Gdi2^tm1b(EUCOMM)Hmgu/Gdi2^tm1b(EUCOMM)Hmgu	C57BL/6N-Gdi2^tm1b(EUCOMM)Hmgu/Ieg	MGI:5757162
ht2	Gdi2^tm1b(EUCOMM)Hmgu/Gdi2^+	C57BL/6N-Gdi2^tm1b(EUCOMM)Hmgu/Ieg	MGI:5785075

Genotype
MGI:5757162

hm1

• Allelic Composition: Gdi2^{tm1b(EUCOMM)Hmgu}/Gdi2^{tm1b(EUCOMM)Hmgu}
• Genetic Background: C57BL/6N-Gdi2^{tm1b(EUCOMM)Hmgu}/Ieg
• Cell Lines: HEPD0749_2_D12

Data Sources

IMPC Data for Gdi2

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

mortality/aging

preweaning lethality, complete penetrance ( J:211773 )

IMPC - HMGU

Genotype
MGI:5785075

ht2

• Allelic Composition: Gdi2^{tm1b(EUCOMM)Hmgu}/Gdi2⁺
• Genetic Background: C57BL/6N-Gdi2^{tm1b(EUCOMM)Hmgu}/Ieg
• Cell Lines: HEPD0749_2_D12

Data Sources

IMPC Data for Gdi2

cardiovascular system

abnormal retina vasculature morphology ( J:211773 )

IMPC - HMGU

homeostasis/metabolism

impaired glucose tolerance ( J:211773 )

♀

IMPC - HMGU

vision/eye

abnormal lens morphology ( J:211773 )

IMPC - HMGU

cataract ( J:211773 )

IMPC - HMGU

abnormal retina morphology ( J:211773 )

♂

IMPC - HMGU

abnormal retina vasculature morphology ( J:211773 )

IMPC - HMGU