Phenotypes associated with this allele

• Allele Symbol: Slc6a2^{tm1b(EUCOMM)Hmgu}
• Allele Name: targeted mutation 1b, Helmholtz Zentrum Muenchen GmbH
• Allele ID: MGI:5588269
• Summary: 2 genotypes

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Slc6a2^tm1b(EUCOMM)Hmgu/Slc6a2^tm1b(EUCOMM)Hmgu	C57BL/6N-Slc6a2^tm1b(EUCOMM)Hmgu/H	MGI:5797823
ht2	Slc6a2^tm1b(EUCOMM)Hmgu/Slc6a2^+	C57BL/6N-Slc6a2^tm1b(EUCOMM)Hmgu/H	MGI:5797822

Genotype
MGI:5797823

hm1

• Allelic Composition: Slc6a2^{tm1b(EUCOMM)Hmgu}/Slc6a2^{tm1b(EUCOMM)Hmgu}
• Genetic Background: C57BL/6N-Slc6a2^{tm1b(EUCOMM)Hmgu}/H
• Cell Lines: HEPD0649_1_F02

Data Sources

IMPC Data for Slc6a2

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

behavior/neurological

abnormal gait ( J:211773 )

♂

IMPC - HAR

cardiovascular system

small heart ( J:211773 )

♀

IMPC - HAR

mortality/aging

preweaning lethality, incomplete penetrance ( J:211773 )

IMPC - HAR

Genotype
MGI:5797822

ht2

• Allelic Composition: Slc6a2^{tm1b(EUCOMM)Hmgu}/Slc6a2⁺
• Genetic Background: C57BL/6N-Slc6a2^{tm1b(EUCOMM)Hmgu}/H
• Cell Lines: HEPD0649_1_F02

Data Sources

IMPC Data for Slc6a2

hematopoietic system

decreased hemoglobin content ( J:211773 )

♂

IMPC - HAR

homeostasis/metabolism

impaired glucose tolerance ( J:211773 )

♂

IMPC - HAR