Phenotypes associated with this allele

• Allele Symbol: Casq2^tm2.1Sgp
• Allele Name: targeted mutation 2.1, Silvia G Priori
• Allele ID: MGI:5587007
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Casq2^tm2.1Sgp/Casq2^tm2.1Sgp	involves: 129	MGI:5587008

Genotype
MGI:5587008

hm1

• Allelic Composition: Casq2^tm2.1Sgp/Casq2^tm2.1Sgp
• Genetic Background: involves: 129

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

cardiovascular system

abnormal myocardial fiber morphology ( J:212671 )

• increased width of junctional sarcoplasmic reticulum in myocytes

• however, adenoviral-mediated expression of the wild-type protein rescues the phenotype

ventricular tachycardia ( J:212671 )

• in all mice

• however, adenoviral-mediated expression of the wild-type protein rescues the phenotype

muscle

abnormal myocardial fiber morphology ( J:212671 )

• increased width of junctional sarcoplasmic reticulum in myocytes

• however, adenoviral-mediated expression of the wild-type protein rescues the phenotype

abnormal sarcoplasmic reticulum morphology ( J:212671 )

• increased width of junctional sarcoplasmic reticulum in myocytes

• however, adenoviral-mediated expression of the wild-type protein rescues the phenotype

cellular

abnormal sarcoplasmic reticulum morphology ( J:212671 )

• increased width of junctional sarcoplasmic reticulum in myocytes

• however, adenoviral-mediated expression of the wild-type protein rescues the phenotype