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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Col1a1tm5(tetO-Jun/Fos)Wag
targeted mutation 5, Erwin F Wagner
MGI:5586534
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
cn1
 		Col1a1tm5(tetO-Jun/Fos)Wag/Col1a1+
Gt(ROSA)26Sortm1(rtTA,EGFP)Nagy/Gt(ROSA)26Sor+
Tg(Alb1-cre)7Gsc/0 		involves: 129 * C57BL/6 * FVB/N MGI:5586561


Genotype
MGI:5586561
cn1
Allelic
Composition		 Col1a1tm5(tetO-Jun/Fos)Wag/Col1a1+
Gt(ROSA)26Sortm1(rtTA,EGFP)Nagy/Gt(ROSA)26Sor+
Tg(Alb1-cre)7Gsc/0
Genetic
Background		 involves: 129 * C57BL/6 * FVB/N
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Col1a1tm5(tetO-Jun/Fos)Wag mutation (0 available); any Col1a1 mutation (166 available)
Gt(ROSA)26Sortm1(rtTA,EGFP)Nagy mutation (5 available); any Gt(ROSA)26Sor mutation (1046 available)
Tg(Alb1-cre)7Gsc mutation (1 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
mortality/aging
premature death ( J:210545 )
• doxycycline-treated mice develop lethal liver dysplasia

liver/biliary system
abnormal liver morphology ( J:210545 )
• doxycycline-treated mice develop lethal liver dysplasia




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
09/30/2025
MGI 6.24 		The Jackson Laboratory