Phenotypes associated with this allele

• Allele Symbol: Mir184^tm1Ics
• Allele Name: targeted mutation 1, Mouse Clinical Institute
• Allele ID: MGI:5584322
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Mir184^tm1Ics/Mir184^tm1Ics	Not Specified	MGI:5585177

Genotype
MGI:5585177

hm1

• Allelic Composition: Mir184^tm1Ics/Mir184^tm1Ics
• Genetic Background: Not Specified

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

homeostasis/metabolism

homeostasis/metabolism phenotype ( J:210552 )

N • mice exhibit normal insulin sensitivity

increased insulin secretion ( J:210552 )

• transient after glucose challenge

decreased fasting circulating glucose level ( J:210552 )

increased circulating insulin level ( J:210552 )

• in fasted mice

improved glucose tolerance ( J:210552 )

• after glucose challenge

endocrine/exocrine glands

increased pancreatic beta cell proliferation ( J:210552 )

increased pancreatic beta cell mass ( J:210552 )

increased insulin secretion ( J:210552 )

• transient after glucose challenge

cellular

increased pancreatic beta cell proliferation ( J:210552 )