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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID
Cables1Tg(CAG-rtTA,CAG-tTS)138Utr
transgene insertion 138, Ken-ichi Yagami
MGI:5581467
Summary 2 genotypes


Genotype
MGI:5581638
hm1
Allelic
Composition
Cables1Tg(CAG-rtTA,CAG-tTS)138Utr/Cables1Tg(CAG-rtTA,CAG-tTS)138Utr
Genetic
Background
CAJcl.Cg-Cables1Tg(CAG-rtTA,CAG-tTS)138Utr
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Cables1Tg(CAG-rtTA,CAG-tTS)138Utr mutation (1 available); any Cables1 mutation (39 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
nervous system
• agenesis in all homozygous mice, which was accompanied by the formation of Probst bundles
• disruption of the dorsal midline zipper glia (MZG) but not of the ventral MZG in forebrains at E18.5




Genotype
MGI:5581639
ht2
Allelic
Composition
Cables1Tg(CAG-rtTA,CAG-tTS)138Utr/Cables1+
Genetic
Background
CAJcl.Cg-Cables1Tg(CAG-rtTA,CAG-tTS)138Utr
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Cables1Tg(CAG-rtTA,CAG-tTS)138Utr mutation (1 available); any Cables1 mutation (39 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
behavior/neurological

nervous system
• abnormalities are reported in the medial position, including the limbic system, but not elsewhere in the forebrain
• agenesis in half of the heterozygous mice, which was accompanied by the formation of Probst bundles





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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
05/07/2024
MGI 6.23
The Jackson Laboratory