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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Ubqln1tm1.1Hmw
targeted mutation 1.1, Hongmin Wang
MGI:5576876
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
cn1
 		Tg(Syn1-cre)671Jxm/0
Ubqln1tm1.1Hmw/Ubqln1tm1.1Hmw 		involves: C57BL/6 * CBA MGI:5576880


Genotype
MGI:5576880
cn1
Allelic
Composition		 Tg(Syn1-cre)671Jxm/0
Ubqln1tm1.1Hmw/Ubqln1tm1.1Hmw
Genetic
Background		 involves: C57BL/6 * CBA
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Tg(Syn1-cre)671Jxm mutation (1 available)
Ubqln1tm1.1Hmw mutation (0 available); any Ubqln1 mutation (22 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
nervous system
abnormal response to CNS ischemic injury ( J:206930 )
• slower recovery of motor function after ischemic injury
increased cerebral infarct size ( J:206930 )
• increased ischemia/reperfusion-caused brain injury in 2 months old animals
abnormal brain morphology ( J:206930 )
• increased accumulation of ubiquitinated-proteins

homeostasis/metabolism
abnormal response to CNS ischemic injury ( J:206930 )
• slower recovery of motor function after ischemic injury
increased cerebral infarct size ( J:206930 )
• increased ischemia/reperfusion-caused brain injury in 2 months old animals




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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
09/30/2025
MGI 6.24 		The Jackson Laboratory