Phenotypes associated with this allele

• Allele Symbol: Gnrhr^tm1Bhr
• Allele Name: targeted mutation 1, Richard R Behringer
• Allele ID: MGI:5576329
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Gnrhr^tm1Bhr/Gnrhr^tm1Bhr	involves: 129S6/SvEvTac * C57BL/6 * C57BL/6J	MGI:5576343

Genotype
MGI:5576343

hm1

• Allelic Composition: Gnrhr^tm1Bhr/Gnrhr^tm1Bhr
• Genetic Background: involves: 129S6/SvEvTac * C57BL/6 * C57BL/6J

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

reproductive system

abnormal ovary morphology ( J:206307 )

♀

impaired ovarian folliculogenesis ( J:206307 )

♀ • no follicular development past the secondary follicle stage

small ovary ( J:206307 )

♀

small seminiferous tubules ( J:206307 )

♂ • mean seminiferous tubule diameter is reduced

small testis ( J:206307 )

♂

abnormal gametogenesis ( J:206307 )

♂

oligozoospermia ( J:206307 )

♂

teratozoospermia ( J:206307 )

♂

abnormal sperm flagellum morphology ( J:206307 )

♂ • looped tails

absent sperm head ( J:206307 )

♂

endocrine/exocrine glands

abnormal ovary morphology ( J:206307 )

♀

impaired ovarian folliculogenesis ( J:206307 )

♀ • no follicular development past the secondary follicle stage

small ovary ( J:206307 )

♀

small seminiferous tubules ( J:206307 )

♂ • mean seminiferous tubule diameter is reduced

small testis ( J:206307 )

♂

cellular

oligozoospermia ( J:206307 )

♂

teratozoospermia ( J:206307 )

♂

abnormal sperm flagellum morphology ( J:206307 )

♂ • looped tails

absent sperm head ( J:206307 )

♂