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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Tbx21tm1.1(flpe/ERT2)Gmld
targeted mutation 1.1, Graham M Lord
MGI:5575639
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
cn1
 		Tbx21tm1.1(flpe/ERT2)Gmld/Tbx21tm1.1(flpe/ERT2)Gmld involves: 129S2/SvPas * C57BL/6 MGI:5575640


Genotype
MGI:5575640
cn1
Allelic
Composition		 Tbx21tm1.1(flpe/ERT2)Gmld/Tbx21tm1.1(flpe/ERT2)Gmld
Genetic
Background		 involves: 129S2/SvPas * C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Tbx21tm1.1(flpe/ERT2)Gmld mutation (0 available); any Tbx21 mutation (36 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
immune system
decreased interferon-gamma secretion ( J:207104 )
• under Th1 promoting conditions, CD4+ T cells transduced with a cre-expressing retrovirus exhibit decreased IFNgamma production compared with controls




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
05/07/2024
MGI 6.23 		The Jackson Laboratory