All Phenotypes Galntl5<tm1Nari> MGI Mouse

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Phenotypes associated with this allele

Allele Symbol
Allele Name
Allele ID

Galntl5^tm1Nari
targeted mutation 1, Hisashi Narimatsu
MGI:5574442

Summary

1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
ht1	Galntl5^tm1Nari/Galntl5⁺	involves: 129P2/OlaHsd * C57BL/6J	MGI:5574447

Allelic Composition	Galntl5^tm1Nari/Galntl5⁺
Genetic Background	involves: 129P2/OlaHsd * C57BL/6J

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Galntl5^tm1Nari mutation (0 available); any Galntl5 mutation (32 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

Deformed or ventral flexuous sperm in Galntl5^tm1Nari/Galntl5⁺ males

reproductive system

abnormal spermatogenesis ( J:206466 )

• abnormal loading of acrosomal proteins, such as acrosin, N-ethylamaleimide-sensitive factor and testicular angiotensin-converting enzyme, to spermatozoa

abnormal acrosome morphology ( J:206466 )

• absence of acrosomal proteins in acrosome and head of sperm

• testicular angiotensin-converting enzyme mislocalized to the sperm outer membrane

• absence of ubiquitin-proteasome system in neck region and acrosome of epididymal sperm

cellular

abnormal acrosome morphology ( J:206466 )

• absence of acrosomal proteins in acrosome and head of sperm

• testicular angiotensin-converting enzyme mislocalized to the sperm outer membrane

• absence of ubiquitin-proteasome system in neck region and acrosome of epididymal sperm

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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