Phenotypes associated with this allele

• Allele Symbol: Tg(Cnp-MAPT*P301L)6Vle
• Allele Name: transgene insertion 6, Virginia M Y Lee
• Allele ID: MGI:5573156
• Summary: 2 genotypes

Jump to	Allelic Composition	Genetic Background	Genotype ID
cx1	Tg(Cnp-MAPT*P301L)6Vle/0 Tg(Cnp-SNCA)M2Vle/0	involves: C3H * C57BL/6	MGI:5573158
tg2	Tg(Cnp-MAPT*P301L)6Vle/0	involves: C3H * C57BL/6	MGI:5573157

Genotype
MGI:5573158

cx1

• Allelic Composition: Tg(Cnp-MAPT*P301L)6Vle/0; Tg(Cnp-SNCA)M2Vle/0
• Genetic Background: involves: C3H * C57BL/6

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

behavior/neurological

jerky movement ( J:127923 )

• limb-twitch phenotype

nervous system

tau protein deposits ( J:127923 )

• mice exhibit accumulation of tau and alpha-synuclein amyloidogenic inclusions in oligodendrocytes as early as 12 months of age

alpha-synuclein inclusion body ( J:127923 )

• mice exhibit accumulation of tau and alpha-synuclein amyloidogenic inclusions in oligodendrocytes as early as 12 months of age

Genotype
MGI:5573157

tg2

• Allelic Composition: Tg(Cnp-MAPT*P301L)6Vle/0
• Genetic Background: involves: C3H * C57BL/6

nervous system

nervous system phenotype ( J:127923 )

N • mice do not develop tau or alpha-synuclein inclusions at 18 months of age