Phenotypes associated with this allele

• Allele Symbol: Aspm^tm1.2Kxi
• Allele Name: targeted mutation 1.2, Kyoko Itoh
• Allele ID: MGI:5573152
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Aspm^tm1.2Kxi/Aspm^tm1.2Kxi	involves: C57BL * C57BL/6J * DBA	MGI:5573161

Genotype
MGI:5573161

hm1

• Allelic Composition: Aspm^tm1.2Kxi/Aspm^tm1.2Kxi
• Genetic Background: involves: C57BL * C57BL/6J * DBA

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

reproductive system

oligozoospermia ( J:205524 )

• decreased number of sperms, spermatids, spermatocytes and spermatogonia

abnormal Sertoli cell morphology ( J:205524 )

• vacuolated

seminiferous tubule degeneration ( J:205524 )

• atrophy

increased Leydig cell number ( J:205524 )

• in the interstitium

small testis ( J:205524 )

nervous system

decreased brain weight ( J:205524 )

enlarged lateral ventricles ( J:205524 )

abnormal cerebral hemisphere morphology ( J:205524 )

• reduced volume

abnormal barrel cortex morphology ( J:205524 )

• in the barrel field, layer I is larger while layer VI is smaller than in wild-type mice

thin cerebral cortex ( J:205524 )

endocrine/exocrine glands

abnormal Sertoli cell morphology ( J:205524 )

• vacuolated

seminiferous tubule degeneration ( J:205524 )

• atrophy

increased Leydig cell number ( J:205524 )

• in the interstitium

small testis ( J:205524 )

cellular

oligozoospermia ( J:205524 )

• decreased number of sperms, spermatids, spermatocytes and spermatogonia