Analysis Tools
normal phenotype
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• mice do not show any developmental or growth defects with normal Cd4 to CD8 ratio
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Allele Symbol Allele Name Allele ID |
Patz1tm1.2Welm targeted mutation 1.2, Wilfried Ellmeier MGI:5572819 |
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| Summary |
3 genotypes
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| ♀ | phenotype observed in females |
| ♂ | phenotype observed in males |
| N | normal phenotype |
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• mice do not show any developmental or growth defects with normal Cd4 to CD8 ratio
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| ♀ | phenotype observed in females |
| ♂ | phenotype observed in males |
| N | normal phenotype |
| N |
• mice subjected to systemic anaphylaxis exhibit normal histamine release response of mast cells in vivo
• mice exhibit normal cutaneous anaphylaxis response
• bone marrow-derived mast cells exhibit normal early and late effector functions upon Fcer1-mediated activation
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• bone marrow cultures yield less bone marrow-derived mast cells compared with wild-type cultures
• however, in vivo numbers of mast cells in the ear skin are normal
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• in bone marrow-derived mast cells activated with TNP
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• bone marrow cultures yield less bone marrow-derived mast cells compared with wild-type cultures
• however, in vivo numbers of mast cells in the ear skin are normal
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• bone marrow cultures yield less bone marrow-derived mast cells compared with wild-type cultures
• however, in vivo numbers of mast cells in the ear skin are normal
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| ♀ | phenotype observed in females |
| ♂ | phenotype observed in males |
| N | normal phenotype |
| N |
• mice exhibit normal numbers of peritoneal mast cells
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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 05/07/2024 MGI 6.23 |
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