Phenotypes associated with this allele
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Find Mice |
Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Lmnatm10Lgf mutation
(0 available);
any
Lmna mutation
(82 available)
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mortality/aging
N |
• mice exhibit normal viability
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nervous system
N |
• mice exhibit normal brain size and morphology
|
behavior/neurological
N |
• mice exhibit normal behavior and performance on a rotarod
|
|
Find Mice |
Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Lmnatm10Lgf mutation
(0 available);
any
Lmna mutation
(82 available)
Zmpste24tm1Sgy mutation
(2 available);
any
Zmpste24 mutation
(32 available)
|
|
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digestive/alimentary system
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• esophagus shows a cornified squamous epithelium
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• mice develop dilated, yellow esophagus
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• thinning and fibrosis of the muscularis externa, pathology similar to achalasia
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muscle
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• thinning and fibrosis of the muscularis externa, pathology similar to achalasia
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nervous system
N |
• mice show no pathology in the central nervous system
|