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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Adam17tm1.2Wesh
targeted mutation 1.2, Wei Shi
MGI:5571392
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		Adam17tm1.2Wesh/Adam17tm1.2Wesh involves: 129 * BALB/cJ * C57BL/6 * FVB/N MGI:5571467


Genotype
MGI:5571467
hm1
Allelic
Composition		 Adam17tm1.2Wesh/Adam17tm1.2Wesh
Genetic
Background		 involves: 129 * BALB/cJ * C57BL/6 * FVB/N
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Adam17tm1.2Wesh mutation (0 available); any Adam17 mutation (62 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
mortality/aging

respiratory system
pulmonary hypoplasia ( J:210193 )
• in neonates

cardiovascular system
increased heart ventricle size ( J:210193 )
• with deep intertrabecular recesses

vision/eye




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
09/30/2025
MGI 6.24 		The Jackson Laboratory