Phenotypes associated with this allele

• Allele Symbol: Sufu^{tm1b(KOMP)Wtsi}
• Allele Name: targeted mutation 1b, Wellcome Trust Sanger Institute
• Allele ID: MGI:5569947
• Summary: 2 genotypes

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Sufu^tm1b(KOMP)Wtsi/Sufu^tm1b(KOMP)Wtsi	C57BL/6N-Sufu^tm1b(KOMP)Wtsi/Ucd	MGI:5701003
ht2	Sufu^tm1b(KOMP)Wtsi/Sufu^+	C57BL/6N-Sufu^tm1b(KOMP)Wtsi/Ucd	MGI:5797851

Genotype
MGI:5701003

hm1

• Allelic Composition: Sufu^{tm1b(KOMP)Wtsi}/Sufu^{tm1b(KOMP)Wtsi}
• Genetic Background: C57BL/6N-Sufu^{tm1b(KOMP)Wtsi}/Ucd
• Cell Lines: EPD0702_3_A09

Data Sources

IMPC Data for Sufu

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

embryo

embryonic growth retardation ( J:211773 )

IMPC - TCP

abnormal embryo size ( J:211773 )

IMPC - TCP

abnormal limb bud morphology ( J:211773 )

♂

IMPC - TCP

abnormal neural tube closure ( J:211773 )

IMPC - TCP

abnormal placenta size ( J:211773 )

♂

IMPC - TCP

pale yolk sac ( J:211773 )

♂

IMPC - TCP

growth/size/body

embryonic growth retardation ( J:211773 )

IMPC - TCP

abnormal embryo size ( J:211773 )

IMPC - TCP

integument

pallor ( J:211773 )

♂

IMPC - TCP

limbs/digits/tail

abnormal limb bud morphology ( J:211773 )

♂

IMPC - TCP

liver/biliary system

abnormal liver size ( J:211773 )

♂

IMPC - TCP

pale liver ( J:211773 )

♂

IMPC - TCP

mortality/aging

embryonic lethality prior to tooth bud stage ( J:211773 )

IMPC - TCP

preweaning lethality, complete penetrance ( J:211773 )

IMPC - TCP

nervous system

abnormal neural tube closure ( J:211773 )

IMPC - TCP

abnormal forebrain development ( J:211773 )

IMPC - TCP

abnormal hindbrain development ( J:211773 )

IMPC - TCP

abnormal midbrain development ( J:211773 )

IMPC - TCP

vision/eye

abnormal eye morphology ( J:211773 )

♂

IMPC - TCP

Genotype
MGI:5797851

ht2

• Allelic Composition: Sufu^{tm1b(KOMP)Wtsi}/Sufu⁺
• Genetic Background: C57BL/6N-Sufu^{tm1b(KOMP)Wtsi}/Ucd
• Cell Lines: EPD0702_3_A09

Data Sources

IMPC Data for Sufu

adipose tissue

decreased total body fat amount ( J:211773 )

♀

IMPC - TCP

behavior/neurological

increased startle reflex ( J:211773 )

♂

IMPC - TCP

cardiovascular system

cardiovascular system phenotype ( J:211773 )

♀

IMPC - TCP

digestive/alimentary system

abnormal stomach morphology ( J:211773 )

♂

IMPC - TCP

immune system

enlarged lymph nodes ( J:211773 )

♂

IMPC - TCP