All Phenotypes Setd1b<tm1.1Afst> MGI Mouse

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Phenotypes associated with this allele

Allele Symbol
Allele Name
Allele ID

Setd1b^tm1.1Afst
targeted mutation 1.1, A Francis Stewart
MGI:5568943

Summary

1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Setd1b^tm1.1Afst/Setd1b^tm1.1Afst	involves: 129S1/Sv * 129X1/SvJ * C57BL/6	MGI:5568955

Allelic Composition	Setd1b^tm1.1Afst/Setd1b^tm1.1Afst
Genetic Background	involves: 129S1/Sv * 129X1/SvJ * C57BL/6

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Setd1b^tm1.1Afst mutation (0 available); any Setd1b mutation (49 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

mortality/aging

embryonic lethality during organogenesis, complete penetrance ( J:208420 )

• by E11.5

embryo

embryonic growth retardation ( J:208420 )

• from E7.5 until embryos died at ~E11.5

growth/size/body

embryonic growth retardation ( J:208420 )

• from E7.5 until embryos died at ~E11.5

cellular

cellular phenotype ( J:208420 )

N	• at E10.5 global H3K4 methylation is not affected

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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