All Phenotypes Setd1b<tm1.1Afst> MGI Mouse

About Help FAQ

Phenotypes associated with this allele

Allele Symbol
Allele Name
Allele ID

Setd1b^tm1.1Afst
targeted mutation 1.1, A Francis Stewart
MGI:5568943

Summary

1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Setd1b^tm1.1Afst/Setd1b^tm1.1Afst	involves: 129S1/Sv * 129X1/SvJ * C57BL/6	MGI:5568955

Allelic Composition	Setd1b^tm1.1Afst/Setd1b^tm1.1Afst
Genetic Background	involves: 129S1/Sv * 129X1/SvJ * C57BL/6

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Setd1b^tm1.1Afst mutation (0 available); any Setd1b mutation (51 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

mortality/aging

embryonic lethality during organogenesis, complete penetrance ( J:208420 )

• by E11.5

embryo

embryonic growth retardation ( J:208420 )

• from E7.5 until embryos died at ~E11.5

growth/size/body

embryonic growth retardation ( J:208420 )

• from E7.5 until embryos died at ~E11.5

cellular

cellular phenotype ( J:208420 )

N	• at E10.5 global H3K4 methylation is not affected

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 09/30/2025 MGI 6.24