Phenotypes associated with this allele

• Allele Symbol: Il17re^tm1Sdl
• Allele Name: targeted mutation 1, Steven D Levin
• Allele ID: MGI:5568616
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Il17re^tm1Sdl/Il17re^tm1Sdl	involves: C57BL/6	MGI:5568617

Genotype
MGI:5568617

hm1

• Allelic Composition: Il17re^tm1Sdl/Il17re^tm1Sdl
• Genetic Background: involves: C57BL/6

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

immune system

increased susceptibility to bacterial infection ( J:178966 )

• mice show increased susceptibility to Citrobacter rodentium infection, showing increased spleen and intestine weights, bacterial numbers as much as 100-fold greater in the spleen, colon and feces, and structural disruption of the colon epithelium

increased susceptibility to bacterial infection induced morbidity/mortality ( J:178966 )

• mice challenged with Citrobacter rodentium begin to lose weight and die by day 13 of infection

mortality/aging

increased susceptibility to bacterial infection induced morbidity/mortality ( J:178966 )

• mice challenged with Citrobacter rodentium begin to lose weight and die by day 13 of infection