Phenotypes associated with this allele

• Allele Symbol: Dab1^scm-5J
• Allele Name: scrambler 5 Jackson
• Allele ID: MGI:5568221
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Dab1^scm-5J/Dab1^scm-5J	BKS(Cg)-Dab1^scm-5J/GrsrJ	MGI:5568261

Genotype
MGI:5568261

hm1

• Allelic Composition: Dab1^scm-5J/Dab1^scm-5J
• Genetic Background: BKS(Cg)-Dab1^scm-5J/GrsrJ

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

nervous system

abnormal hippocampus morphology ( J:209638 )

• histology shows scrambled arrangement in the cerebral cortex, hippocampus, and cerebellum

abnormal cerebral cortex morphology ( J:209638 )

• histology shows scrambled arrangement in the cerebral cortex, hippocampus, and cerebellum

abnormal cerebellar layer morphology ( J:209638 )

• histology shows scrambled arrangement in the cerebral cortex, hippocampus, and cerebellum

behavior/neurological

abnormal motor coordination/balance ( J:209638 )

• homozygotes are severely unstable in their gait and unable to right themselves at about 2 weeks of age

impaired righting response ( J:209638 )

ataxia ( J:209638 )

weakness ( J:209638 )

abnormal gait ( J:209638 )

• homozygotes are severely unstable in their gait and unable to right themselves at about 2 weeks of age

growth/size/body

thin body ( J:209638 )

• homozygotes are thin and weak

mortality/aging

lethality at weaning, complete penetrance ( J:209638 )

• all homozygotes die by 4 weeks of age

postnatal lethality, incomplete penetrance ( J:209638 )

• nearly all homozygotes die by approximately 3 weeks of age