All Phenotypes Jak2<tm2.1Kpf> MGI Mouse

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Phenotypes associated with this allele

Allele Symbol
Allele Name
Allele ID

Jak2^tm2.1Kpf
targeted mutation 2.1, Klaus Pfeffer
MGI:5566794

Summary

1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Jak2^tm2.1Kpf/Jak2^tm2.1Kpf	involves: 129P2/OlaHsd	MGI:5566799

Allelic Composition	Jak2^tm2.1Kpf/Jak2^tm2.1Kpf
Genetic Background	involves: 129P2/OlaHsd

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Jak2^tm2.1Kpf mutation (0 available); any Jak2 mutation (60 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

mortality/aging

• mice die at E12.5

hematopoietic system

abnormal embryonic erythropoiesis ( J:207710 )

• absent

integument

pallor ( J:207710 )

• pale embryo

liver/biliary system

small liver ( J:207710 )

• reduced mass

cellular

abnormal cell physiology ( J:207710 )

• mouse embryonic fibroblasts exhibit a 6-fold reduction in vaccinia virus replication compared with wild-type cells

embryo

abnormal embryonic erythropoiesis ( J:207710 )

• absent

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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