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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Dicer1em2Psv
endonuclease-mediated mutation 2, Petr Svoboda
MGI:5566697
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		Dicer1em2Psv/Dicer1em2Psv involves: C57BL/6NCrl MGI:5566700


Genotype
MGI:5566700
hm1
Allelic
Composition		 Dicer1em2Psv/Dicer1em2Psv
Genetic
Background		 involves: C57BL/6NCrl
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Dicer1em2Psv mutation (0 available); any Dicer1 mutation (94 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
reproductive system
reproductive system phenotype ( J:203415 )
N
• males are fertile
abnormal female meiosis ( J:203415 )
• meiotic spindle defects and increased levels of endo-siRNA targets
abnormal spindle assembly in female meiosis ( J:203415 )
• meiotic spindle defects in oocytes

cellular
abnormal female meiosis ( J:203415 )
• meiotic spindle defects and increased levels of endo-siRNA targets
abnormal spindle assembly in female meiosis ( J:203415 )
• meiotic spindle defects in oocytes




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
04/30/2024
MGI 6.23 		The Jackson Laboratory