All Phenotypes Elavl1<tm1.1Atas> MGI Mouse

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Phenotypes associated with this allele

Allele Symbol
Allele Name
Allele ID

Elavl1^tm1.1Atas
targeted mutation 1.1, Ulus Atasoy
MGI:5563910

Summary

1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
cn1	Elavl1^tm1.1Atas/Elavl1^tm1.1Atas Tnfrsf4^tm2(cre)Nik/Tnfrsf4⁺	involves: 129X1/SvJ * C57BL/6	MGI:5566528

Allelic Composition	Elavl1^tm1.1Atas/Elavl1^tm1.1Atas Tnfrsf4^tm2(cre)Nik/Tnfrsf4⁺
Genetic Background	involves: 129X1/SvJ * C57BL/6

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Elavl1^tm1.1Atas mutation (0 available); any Elavl1 mutation (42 available)
Tnfrsf4^tm2(cre)Nik mutation (1 available); any Tnfrsf4 mutation (24 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

immune system

decreased T cell proliferation ( J:207013 )

• slightly under Th17-polarizing conditions

decreased T-helper 17 cell number ( J:207013 )

decreased susceptibility to experimental autoimmune encephalomyelitis ( J:207013 )

• adoptive transfer of CD4+ Th17 cells immunized with MOG results in delayed onset and reduced severity of experimental autoimmune encephalomyelitis with reduced in recipient mice compared with when wild-type cells are transferred

hematopoietic system

decreased T cell proliferation ( J:207013 )

• slightly under Th17-polarizing conditions

decreased T-helper 17 cell number ( J:207013 )

cellular

decreased T cell proliferation ( J:207013 )

• slightly under Th17-polarizing conditions

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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