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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID
Tg(Gt(ROSA)26Sor-Ndufa5)#Ctm
transgene insertion, Carlos T Moraes
MGI:5563661
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
cn1
Ndufa5Gt(RRK279)Byg/Ndufa5Gt(RRK279)Byg
Tg(Camk2a-cre)#Szi/0
Tg(Gt(ROSA)26Sor-Ndufa5)#Ctm/0
involves: 129P2/OlaHsd * C57BL/6J * CBA * SJL MGI:5563770


Genotype
MGI:5563770
cn1
Allelic
Composition
Ndufa5Gt(RRK279)Byg/Ndufa5Gt(RRK279)Byg
Tg(Camk2a-cre)#Szi/0
Tg(Gt(ROSA)26Sor-Ndufa5)#Ctm/0
Genetic
Background
involves: 129P2/OlaHsd * C57BL/6J * CBA * SJL
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Ndufa5Gt(RRK279)Byg mutation (0 available); any Ndufa5 mutation (13 available)
Tg(Camk2a-cre)#Szi mutation (0 available)
Tg(Gt(ROSA)26Sor-Ndufa5)#Ctm mutation (0 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
behavior/neurological
• at 10 to 11 months
• at 10 to 11 months
• at 10 to 11 months, mice exhibit longer latency in a pole descent test and reduced motor coordination in the grid and beam-walking tests compared with control mice

cellular
• mice exhibit complex I deficiency in the cortex compared with wild-type mice

nervous system
N
• at 11 months, cortex morphology is normal without oxidative damage





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last database update
05/14/2024
MGI 6.23
The Jackson Laboratory