About   Help   FAQ
Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Dock2m2Anu
mutation 2, Australian National University
MGI:5563490
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		Dock2m2Anu/Dock2m2Anu C57BL/6JAnu-Dock2m2Anu MGI:5564959


Genotype
MGI:5564959
hm1
Allelic
Composition		 Dock2m2Anu/Dock2m2Anu
Genetic
Background		 C57BL/6JAnu-Dock2m2Anu
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Dock2m2Anu mutation (2 available); any Dock2 mutation (142 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
hematopoietic system
decreased mature B cell number ( J:104190 )
• in peripheral blood
abnormal T cell morphology ( J:104190 )
• reduced CD44 protein expression on CD4+ and CD8+ cells
decreased T cell number ( J:104190 )
• in peripheral blood

immune system
decreased mature B cell number ( J:104190 )
• in peripheral blood
abnormal T cell morphology ( J:104190 )
• reduced CD44 protein expression on CD4+ and CD8+ cells
decreased T cell number ( J:104190 )
• in peripheral blood




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
05/07/2024
MGI 6.23 		The Jackson Laboratory