About   Help   FAQ
Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Inpp5dm1Anu
mutation 1, Australian National University
MGI:5563462
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		Inpp5dm1Anu/Inpp5dm1Anu C57BL/6JAnu-Inpp5dm1Anu MGI:5564957


Genotype
MGI:5564957
hm1
Allelic
Composition		 Inpp5dm1Anu/Inpp5dm1Anu
Genetic
Background		 C57BL/6JAnu-Inpp5dm1Anu
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Inpp5dm1Anu mutation (1 available); any Inpp5d mutation (95 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
respiratory system
lung hemorrhage ( J:104190 )
• scattered microhaemorrhages associated with pneumonia
lung inflammation ( J:104190 )
• intra-alveolar acidophilic macrophage pneumonia with scattered microhaemorrhages
• superimposed recent suppurative bronchiolar pneumonia with microabscesses and early bronchitis

neoplasm
increased B cell derived lymphoma incidence ( J:104190 )
• histiocytic (B cell) lymphoma involving mediastinal lymph nodes, lung, spleen and small intestine

cardiovascular system
lung hemorrhage ( J:104190 )
• scattered microhaemorrhages associated with pneumonia

immune system
lung inflammation ( J:104190 )
• intra-alveolar acidophilic macrophage pneumonia with scattered microhaemorrhages
• superimposed recent suppurative bronchiolar pneumonia with microabscesses and early bronchitis




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
09/30/2025
MGI 6.24 		The Jackson Laboratory