Phenotypes associated with this allele

• Allele Symbol: Axin2^M1J
• Allele Name: mutation 1, Jackson
• Allele ID: MGI:5563343
• Summary: 2 genotypes

Jump to	Allelic Composition	Genetic Background	Genotype ID
ht1	Axin2^M1J/Axin2^+	C57BL/6J-Axin2^M1J/GrsrJ	MGI:5659868
ht2	Axin2^M1J/Axin2^+	involves: C57BL/6J * FVB/NJ	MGI:5659869

Genotype
MGI:5659868

ht1

• Allelic Composition: Axin2^M1J/Axin2⁺
• Genetic Background: C57BL/6J-Axin2^M1J/GrsrJ

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

limbs/digits/tail

kinked tail ( J:223644 )

• heterozygotes have a noticably kinked tail and the tail length varies with the amount of kinking of the tail

mortality/aging

prenatal lethality, incomplete penetrance ( J:223644 )

• fewer than the expected number of heterozygotes are produced from C57BL/6J x heterozygote or heterozygote x C57BL/6J crosses

Genotype
MGI:5659869

ht2

• Allelic Composition: Axin2^M1J/Axin2⁺
• Genetic Background: involves: C57BL/6J * FVB/NJ

limbs/digits/tail

kinked tail ( J:223644 )

mortality/aging

prenatal lethality, incomplete penetrance ( J:223644 )

• on an F1 background of C57BL/6J and FVB/NJ only 13 of 8 offspring from heterozygote x wildtype had tail kinks and when these were backcrossed to C57BL/6J for a background of approximately 75% C57BL/6J only 33 of 91 had tail kinks