All Phenotypes Vps4a<tm1b(EUCOMM)Hmgu> MGI Mouse

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Phenotypes associated with this allele

Allele Symbol
Allele Name
Allele ID

Vps4a^{tm1b(EUCOMM)Hmgu}
targeted mutation 1b, Helmholtz Zentrum Muenchen GmbH
MGI:5561562

Summary

2 genotypes

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Vps4a^{tm1b(EUCOMM)Hmgu}/Vps4a^{tm1b(EUCOMM)Hmgu}	C57BL/6N-Vps4a^{tm1b(EUCOMM)Hmgu}/Bay	MGI:5757881
ht2	Vps4a^{tm1b(EUCOMM)Hmgu}/Vps4a⁺	C57BL/6N-Vps4a^{tm1b(EUCOMM)Hmgu}/Bay	MGI:5757880

Allelic Composition	Vps4a^{tm1b(EUCOMM)Hmgu}/Vps4a^{tm1b(EUCOMM)Hmgu}
Genetic Background	C57BL/6N-Vps4a^{tm1b(EUCOMM)Hmgu}/Bay
Cell Lines	HEPD0779_2_A10

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Vps4a^{tm1b(EUCOMM)Hmgu} mutation (0 available); any Vps4a mutation (15 available)

Data Sources

IMPC Data for Vps4a

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

behavior/neurological

unresponsive to tactile stimuli ( J:211773 )

IMPC - BCM

craniofacial

protruding tongue ( J:211773 )

IMPC - BCM

digestive/alimentary system

protruding tongue ( J:211773 )

IMPC - BCM

embryo

abnormal embryo size ( J:211773 )

IMPC - BCM

growth/size/body

protruding tongue ( J:211773 )

IMPC - BCM

abnormal embryo size ( J:211773 )

IMPC - BCM

abnormal body wall morphology ( J:211773 )

IMPC - BCM

mortality/aging

preweaning lethality, complete penetrance ( J:211773 )

IMPC - BCM

Allelic Composition	Vps4a^{tm1b(EUCOMM)Hmgu}/Vps4a⁺
Genetic Background	C57BL/6N-Vps4a^{tm1b(EUCOMM)Hmgu}/Bay
Cell Lines	HEPD0779_2_A10

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Vps4a^{tm1b(EUCOMM)Hmgu} mutation (0 available); any Vps4a mutation (15 available)

Data Sources

IMPC Data for Vps4a

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

behavior/neurological

unresponsive to tactile stimuli ( J:211773 )

IMPC - BCM

tremors ( J:211773 )

IMPC - BCM

growth/size/body

enlarged spleen ( J:211773 )

IMPC - BCM

increased spleen weight ( J:211773 )

IMPC - BCM

hematopoietic system

enlarged spleen ( J:211773 )

IMPC - BCM

increased spleen weight ( J:211773 )

IMPC - BCM

immune system

enlarged spleen ( J:211773 )

IMPC - BCM

increased spleen weight ( J:211773 )

IMPC - BCM

integument

abnormal skin morphology ( J:211773 )

IMPC - BCM

vision/eye

abnormal lens morphology ( J:211773 )

IMPC - BCM

cataract ( J:211773 )

IMPC - BCM

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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