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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Stra8tm1Ysa
targeted mutation 1,Yumiko Saga
MGI:5561006
Summary 3 genotypes
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		Stra8tm1Ysa/Stra8tm1Ysa involves: C57BL/6NCrlj * CBA/JNCrlj * Jcl:MCH(ICR) MGI:5561051
cx2
 		Nanos2tm1Ysa/Nanos2tm1Ysa
Stra8tm1Ysa/Stra8+ 		involves: 129 * C57BL/6NCrlj * CBA/JNCrlj * Jcl:MCH(ICR) MGI:5561055
cx3
 		Nanos2tm1Ysa/Nanos2tm1Ysa
Stra8tm1Ysa/Stra8tm1Ysa 		involves: 129 * C57BL/6NCrlj * CBA/JNCrlj * Jcl:MCH(ICR) MGI:5561053


Genotype
MGI:5561051
hm1
Allelic
Composition		 Stra8tm1Ysa/Stra8tm1Ysa
Genetic
Background		 involves: C57BL/6NCrlj * CBA/JNCrlj * Jcl:MCH(ICR)
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Stra8tm1Ysa mutation (0 available); any Stra8 mutation (36 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
reproductive system
abnormal female meiosis ( J:205334 )
• defect in progression

cellular
abnormal female meiosis ( J:205334 )
• defect in progression




Genotype
MGI:5561055
cx2
Allelic
Composition		 Nanos2tm1Ysa/Nanos2tm1Ysa
Stra8tm1Ysa/Stra8+
Genetic
Background		 involves: 129 * C57BL/6NCrlj * CBA/JNCrlj * Jcl:MCH(ICR)
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Nanos2tm1Ysa mutation (0 available); any Nanos2 mutation (16 available)
Stra8tm1Ysa mutation (0 available); any Stra8 mutation (36 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
reproductive system
abnormal male meiosis ( J:205334 )
• defective
abnormal male reproductive system physiology ( J:205334 )
• male germ cells fail to maintain mitotic arrest and re-enter the cell cycle at E15.5

cellular
abnormal male meiosis ( J:205334 )
• defective




Genotype
MGI:5561053
cx3
Allelic
Composition		 Nanos2tm1Ysa/Nanos2tm1Ysa
Stra8tm1Ysa/Stra8tm1Ysa
Genetic
Background		 involves: 129 * C57BL/6NCrlj * CBA/JNCrlj * Jcl:MCH(ICR)
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Nanos2tm1Ysa mutation (0 available); any Nanos2 mutation (16 available)
Stra8tm1Ysa mutation (0 available); any Stra8 mutation (36 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
reproductive system
abnormal male meiosis ( J:205334 )
• defective
abnormal male reproductive system physiology ( J:205334 )
• male germ cells fail to maintain mitotic arrest and re-enter the cell cycle at E15.5

cellular
abnormal male meiosis ( J:205334 )
• defective




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
09/30/2025
MGI 6.24 		The Jackson Laboratory