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Allele Symbol Allele Name Allele ID |
Gt(ROSA)26Sortm95.1(CAG-GCaMP6f)Hze targeted mutation 95.1, Hongkui Zeng MGI:5558090 |
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| Summary |
2 genotypes
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| ♀ | phenotype observed in females |
| ♂ | phenotype observed in males |
| N | normal phenotype |
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| ♀ | phenotype observed in females |
| ♂ | phenotype observed in males |
| N | normal phenotype |
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• elevated touch withdrawal reflexes in mice injected with a cre-expressing adenovirus
• following induced spared nerve injury, mice injected with a cre-expressing adenovirus fail to exhibit detect brush even 1 week after nerve injury unlike control mice
• absence of responses to dynamic touch stimulation of hind paw in mice injected with a cre-expressing adenovirus
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• following induction of inflammation induced by complete Freunds adjuvant (CFA) or capsaicin, mice injected with a cre-expressing adenovirus exhibit reduced response to brush, air puff and vibration stimuli compared with control mice
• however, response to pinch stimuli is normal
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• neurons in mice injected with a cre-expressing adenovirus fail to exhibit mechanically activated currents unlike control mice
• however, Adelta and C fiber response to high-threshold mechanical stimuli is normal
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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 05/07/2024 MGI 6.23 |
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