All Phenotypes Igs12<tm1Zhu> MGI Mouse

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Phenotypes associated with this allele

Allele Symbol
Allele Name
Allele ID

Igs12^tm1Zhu
targeted mutation 1, Yuan Zhuang
MGI:5557968

Summary

1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
cn1	Dhx9^{Tn(pb-Act-RFP)1.071225026-HRAZhu}/Dhx9⁺ Igs12^tm1Zhu/Igs12^tm1Zhu Ptprc^a/Ptprc^b Tg(Lck-cre)#Zhu/0	involves: 129S6/SvEvTac * C57BL/6 * FVB/NJ * SJL/J	MGI:5557973

Allelic Composition	Dhx9^{Tn(pb-Act-RFP)1.071225026-HRAZhu}/Dhx9⁺ Igs12^tm1Zhu/Igs12^tm1Zhu Ptprc^a/Ptprc^b Tg(Lck-cre)#Zhu/0
Genetic Background	involves: 129S6/SvEvTac * C57BL/6 * FVB/NJ * SJL/J

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Dhx9^{Tn(pb-Act-RFP)1.071225026-HRAZhu} mutation (0 available); any Dhx9 mutation (77 available)
Igs12^tm1Zhu mutation (0 available); any Igs12 mutation (0 available)
Ptprc^a mutation (72 available); any Ptprc mutation (212 available)
Ptprc^b mutation (9 available); any Ptprc mutation (212 available)
Tg(Lck-cre)#Zhu mutation (0 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

immune system

abnormal T cell differentiation ( J:207361 )

• stage-specific alterations in T cell maturation determined by the ratio of Ptprc^a to Ptprc^b expressing cells

hematopoietic system

abnormal T cell differentiation ( J:207361 )

• stage-specific alterations in T cell maturation determined by the ratio of Ptprc^a to Ptprc^b expressing cells

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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