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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Dhx9Tn(pb-Act-RFP)1.071225026-HRAZhu
transposon insertion 1.071225026-HRA, Yuan Zhuang
MGI:5557965
Summary 3 genotypes
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		Dhx9Tn(pb-Act-RFP)1.071225026-HRAZhu/Dhx9Tn(pb-Act-RFP)1.071225026-HRAZhu involves: FVB/NJ MGI:5557971
ht2
 		Dhx9Tn(pb-Act-RFP)1.071225026-HRAZhu/Dhx9+ involves: FVB/NJ MGI:5557972
cn3
 		Dhx9Tn(pb-Act-RFP)1.071225026-HRAZhu/Dhx9+
Igs12tm1Zhu/Igs12tm1Zhu
Ptprca/Ptprcb
Tg(Lck-cre)#Zhu/0 		involves: 129S6/SvEvTac * C57BL/6 * FVB/NJ * SJL/J MGI:5557973


Genotype
MGI:5557971
hm1
Allelic
Composition		 Dhx9Tn(pb-Act-RFP)1.071225026-HRAZhu/Dhx9Tn(pb-Act-RFP)1.071225026-HRAZhu
Genetic
Background		 involves: FVB/NJ
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Dhx9Tn(pb-Act-RFP)1.071225026-HRAZhu mutation (0 available); any Dhx9 mutation (76 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
mortality/aging
prenatal lethality, complete penetrance ( J:207361 )
• no offspring are produced from breeding heterozygotes




Genotype
MGI:5557972
ht2
Allelic
Composition		 Dhx9Tn(pb-Act-RFP)1.071225026-HRAZhu/Dhx9+
Genetic
Background		 involves: FVB/NJ
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Dhx9Tn(pb-Act-RFP)1.071225026-HRAZhu mutation (0 available); any Dhx9 mutation (76 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
immune system
immune system phenotype ( J:207361 )
N
• mice exhibit relatively normal T cell development and homeostasis




Genotype
MGI:5557973
cn3
Allelic
Composition		 Dhx9Tn(pb-Act-RFP)1.071225026-HRAZhu/Dhx9+
Igs12tm1Zhu/Igs12tm1Zhu
Ptprca/Ptprcb
Tg(Lck-cre)#Zhu/0
Genetic
Background		 involves: 129S6/SvEvTac * C57BL/6 * FVB/NJ * SJL/J
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Dhx9Tn(pb-Act-RFP)1.071225026-HRAZhu mutation (0 available); any Dhx9 mutation (76 available)
Igs12tm1Zhu mutation (0 available); any Igs12 mutation (0 available)
Ptprca mutation (51 available); any Ptprc mutation (188 available)
Ptprcb mutation (8 available); any Ptprc mutation (188 available)
Tg(Lck-cre)#Zhu mutation (0 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
immune system
abnormal T cell differentiation ( J:207361 )
• stage-specific alterations in T cell maturation determined by the ratio of Ptprca to Ptprcb expressing cells

hematopoietic system
abnormal T cell differentiation ( J:207361 )
• stage-specific alterations in T cell maturation determined by the ratio of Ptprca to Ptprcb expressing cells




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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
05/14/2024
MGI 6.23 		The Jackson Laboratory