Phenotypes associated with this allele

• Allele Symbol: Dhx9^{Tn(pb-Act-RFP)1.071225026-HRAZhu}
• Allele Name: transposon insertion 1.071225026-HRA, Yuan Zhuang
• Allele ID: MGI:5557965
• Summary: 3 genotypes

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Dhx9^Tn(pb-Act-RFP)1.071225026-HRAZhu/Dhx9^Tn(pb-Act-RFP)1.071225026-HRAZhu	involves: FVB/NJ	MGI:5557971
ht2	Dhx9^Tn(pb-Act-RFP)1.071225026-HRAZhu/Dhx9^+	involves: FVB/NJ	MGI:5557972
cn3	Dhx9^Tn(pb-Act-RFP)1.071225026-HRAZhu/Dhx9^+ Igs12^tm1Zhu/Igs12^tm1Zhu Ptprc^a/Ptprc^b Tg(Lck-cre)#Zhu/0	involves: 129S6/SvEvTac * C57BL/6 * FVB/NJ * SJL/J	MGI:5557973

Genotype
MGI:5557971

hm1

• Allelic Composition: Dhx9^{Tn(pb-Act-RFP)1.071225026-HRAZhu}/Dhx9^{Tn(pb-Act-RFP)1.071225026-HRAZhu}
• Genetic Background: involves: FVB/NJ

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

mortality/aging

prenatal lethality, complete penetrance ( J:207361 )

• no offspring are produced from breeding heterozygotes

Genotype
MGI:5557972

ht2

• Allelic Composition: Dhx9^{Tn(pb-Act-RFP)1.071225026-HRAZhu}/Dhx9⁺
• Genetic Background: involves: FVB/NJ

immune system

immune system phenotype ( J:207361 )

N • mice exhibit relatively normal T cell development and homeostasis

Genotype
MGI:5557973

cn3

• Allelic Composition: Dhx9^{Tn(pb-Act-RFP)1.071225026-HRAZhu}/Dhx9⁺; Igs12^tm1Zhu/Igs12^tm1Zhu; Ptprc^a/Ptprc^b; Tg(Lck-cre)#Zhu/0
• Genetic Background: involves: 129S6/SvEvTac * C57BL/6 * FVB/NJ * SJL/J

immune system

abnormal T cell differentiation ( J:207361 )

• stage-specific alterations in T cell maturation determined by the ratio of Ptprc^a to Ptprc^b expressing cells

hematopoietic system

abnormal T cell differentiation ( J:207361 )

• stage-specific alterations in T cell maturation determined by the ratio of Ptprc^a to Ptprc^b expressing cells