All Phenotypes Tinf2<tm2.1Tdl> MGI Mouse

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Phenotypes associated with this allele

Allele Symbol
Allele Name
Allele ID

Tinf2^tm2.1Tdl
targeted mutation 2.1, Titia de Lange
MGI:5556226

Summary

2 genotypes

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Tinf2^tm2.1Tdl/Tinf2^tm2.1Tdl	involves: C57BL/6	MGI:5556236
cn2	Tinf2^tm2.1Tdl/Tinf2⁺ Tg(CMV-cre)1Cgn/0	involves: BALB/cJ * C57BL/6	MGI:5556240

Allelic Composition	Tinf2^tm2.1Tdl/Tinf2^tm2.1Tdl
Genetic Background	involves: C57BL/6

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Tinf2^tm2.1Tdl mutation (1 available); any Tinf2 mutation (12 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

normal phenotype

no abnormal phenotype detected ( J:207367 )

Allelic Composition	Tinf2^tm2.1Tdl/Tinf2⁺ Tg(CMV-cre)1Cgn/0
Genetic Background	involves: BALB/cJ * C57BL/6

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Tg(CMV-cre)1Cgn mutation (9 available)
Tinf2^tm2.1Tdl mutation (1 available); any Tinf2 mutation (12 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

growth/size/body

decreased birth body size ( J:207367 )

decreased body weight ( J:207367 )

• mice weigh slightly less than wild type littermates at weaning and 6 months of age

mortality/aging

prenatal lethality, incomplete penetrance ( J:207367 )

• mutants are born at a lower than expected frequency (35%)

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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