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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID
Gpr83tm1.2Lex
targeted mutation 1.2, Lexicon Genetics
MGI:5554947
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
hm1
Gpr83tm1.2Lex/Gpr83tm1.2Lex involves: 129 * C57BL/6 MGI:5554950


Genotype
MGI:5554950
hm1
Allelic
Composition
Gpr83tm1.2Lex/Gpr83tm1.2Lex
Genetic
Background
involves: 129 * C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Gpr83tm1.2Lex mutation (0 available); any Gpr83 mutation (23 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
behavior/neurological
N
• mice exhibit normal fear acquisition conditioning and extinction
• delayed acquisition of spatial learning in a Morris water maze
• for sucrose
• following restraint stress
• however, baseline anxiety is normal
• following restraint stress
• however, mice exhibit normal activity in the home cage

homeostasis/metabolism
N
• mice exhibit normal hypothalamic pituitary adrenal axis response following restraint stress





Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
05/14/2024
MGI 6.23
The Jackson Laboratory