All Phenotypes Mapk7<b2b2346Clo> MGI Mouse

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Phenotypes associated with this allele

Allele Symbol
Allele Name
Allele ID

Mapk7^b2b2346Clo
Bench to Bassinet Program (B2B/CVDC), mutation 2346 Cecilia Lo
MGI:5554435

Summary

1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Mapk7^b2b2346Clo/Mapk7^b2b2346Clo	C57BL/6J-Mapk7^b2b2346Clo	MGI:5555839

Allelic Composition	Mapk7^b2b2346Clo/Mapk7^b2b2346Clo
Genetic Background	C57BL/6J-Mapk7^b2b2346Clo

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Mapk7^b2b2346Clo mutation (1 available); any Mapk7 mutation (32 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

Mutant 2346-004-2 (E16.5) exhibits parallel outflow tracts, hypoplastic transverse arch, and thin ventricles which is diagnosed as DORV and ventricular non-compaction by EFIC imaging

cardiovascular system

abnormal myocardium compact layer morphology ( J:175213 )

• excessive myocardial trabeculation or noncompaction

double outlet right ventricle ( J:175213 )

double outlet right ventricle with atrioventricular septal defect ( J:175213 )

atrioventricular septal defect ( J:175213 )

ventricular septal defect ( J:175213 )

muscular ventricular septal defect ( J:175213 )

renal/urinary system

polycystic kidney ( J:175213 )

hydronephrosis ( J:175213 )

muscle

abnormal myocardium compact layer morphology ( J:175213 )

• excessive myocardial trabeculation or noncompaction

growth/size/body

polycystic kidney ( J:175213 )

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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